Nanowire arrays interfaced with biological cells have been demonstrated to be potent tools for advanced applications such as sensing, stimulation, or drug delivery. This study published in Advanced Materials Interfaces demonstrates the generation of functional human iPSC-derived neurons on nanowire arrays with varying geometrical specifications. The cell/nanowire interactions range from fakir-like states to nanowire-encapsulating states depending on the array characteristics. The neurons are functional with similar kinetics of the action potentials highlighting the equivalence of the nanowire arrays for neuronal differentiation.
We are conducting research in the fields of nanoscience and nanotechnology. Specifically, we investigate quantum transport in van der Waals materials, nanomaterial growth, and application of nanostructured materials in photonics, electronics, mechanics, bio-circuits.
The CHyN is registered as a ‘Gerätezentrum’ of the Deutsche Forschungsgemeinschaft (DFG) under code RI_00477.
- Stem cell-derived neurons on nanowire array
- Opening: Master and Bachelor
- Our research in the Universität Hamburg magazine „19NEUNZEHN“
- Press Release by Nanoscribe – Cell-culture microarchitectures for 3D neuronal networks
- Tech Note – Together with Zeiss – Fabrication and Characterization of Nanofluidic Devices for DNA Optical Mapping